ADSR may refer to:

• Synthesizer#ADSR envelope (ADSR envelope, Attack-Decay-Sustain-Release), a term referring to the amplitude envelope used in some synthesizers
• Accelerator-driven sub-critical reactor, a nuclear reactor using a particle accelerator to generate a fission reaction in a sub-critical assembly of fissionable material
• A.D.S.R. Musicwerks, a Seattle, Washington store and US record label that releases Synth Pop and Electro Industrial music
• Attack Decay Sustain Release, the debut album from Simian Mobile Disco, released on June 18, 2007