AFL may refer to:

• American Federation of Labor, one of the first federations of labor unions in the United States, and now part of the AFL-CIO
• American Football League (a.k.a. "AFL IV") - a professional American football league that started competition in 1960, and merged with the National Football League (NFL) in 1970
• Arena Football League, an American indoor football league
• Australian Football League

AFL may also refer to:

Other sports leagues

• American Fencing League, a league for amateur standard fencing competition in the United States
• American Fight League An American mixed martial arts company founded in 2006
• American Football League (AFL), a name shared by several separate and unrelated professional American football leagues:
  • American Football League (1926) (a.k.a. "AFL I") - first rival of the National Football League (NFL) that competed in 1926
  • American Football League (1934) - regional borderline-major league that competed in 1934
  • American Football League (1936) (a.k.a. "AFL II") - second rival of the NFL that competed in 1936 and 1937
  • American Football League (1938) - minor professional American football league that changed its name to the American Professional Football Association in 1939
  • American Football League (1940) (a.k.a. "AFL III") - third rival of the NFL that competed in 1940 and 1941
  • American Football League (1944) - offshoot of the Pacific Coast Professional Football League, played one year before merging back with the PCPFL
  • American Football League (1946) - name adopted by the American Association minor American football league in 1946
• Arizona Fall League, American baseball league

Other

• Abstract family of languages
• Academic Free License
• Aeroflot, ICAO airline code
• AFL (video game series)
• Aflac New York Stock Exchange abbreviation for, an American insurance company
• Alberta Federation of Labour
• Alta Floresta, Brazil IATA airport code
• Ankara Fen Lisesi, more widely known as Ankara Science High School
• Anti-Football League, an organisation that bemoans the cultural saturation of the Australian Football League
• Armed Forces of Liberia
• Assessment for Learning
• Astrobiology Field Laboratory, a proposed and consequently cancelled (unfunded) robotic rover to be sent to planet Mars

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