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APOA5

Apolipoprotein A-V is a protein that in humans is encoded by the APOA5 gene.[1][2][3]

The protein encoded by this gene is an apolipoprotein and an important determinant of plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of several lipoprotein fractions including VLDL, HDL, chylomicrons. It is believed that apoA-V affects lipoprotein metabolism by interacting with LDL-R gene family receptors.[4]

This gene uses alternate polyadenylation sites and is located proximal to the apolipoprotein gene cluster on chromosome 11q23.[3]

Contents


Interactive pathway map

See also

References

Further reading

ru: A5






Source: Wikipedia | The above article is available under the GNU FDL. | Edit this article



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