The ASTEROID trial was a clinical trial published in 2006 that shows the effects of statins (drugs that inhibit the enzyme HMG-CoA reductase) on atherosclerosis. Employing intravascular ultrasound (IVUS), they showed regression of the atherosclerotic plaques in response to a high dose of rosuvastatin^[1]

References

1. ↑ Nissen SE, Nicholls SJ, Sipahi I, Libby P, Raichlen JS, Ballantyne CM, Davignon J, Erbel R, Fruchart JC, Tardif JC, Schoenhagen P, Crowe T, Cain V, Wolski K, Goormastic M, Tuzcu EM; ASTEROID Investigators. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA 2006;295:1556-65. PMID 16533939.