In enzymology, an ATP deaminase () is an enzyme that catalyzes the chemical reaction

ATP + H₂O \rightleftharpoons ITP + NH₃

Thus, the two substrates of this enzyme are ATP and H₂O, whereas its two products are ITP and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is ATP aminohydrolase. This enzyme is also called adenosine triphosphate deaminase.

References