Ace of Hearts may refer to:

• One of the 52 standard playing cards
• The Ace of Hearts (1921 film), a silent film starring Lon Chaney, Sr.
• Ace of Hearts (2008 film), directed by David Mackay
• Ace of Hearts Records, a budget record label owned by Decca records
• Ace of Hearts Records (Boston), a Boston-based record label started in 1978
• "Ace of Hearts", a song on the 1984 album Wired to the Moon by Chris Rea
• Ace of Hz, a song by Ladytron