An acidophile (or acidophil, or, as an adjectival form, acidophilic) describes is a term used by histologists to describe a particular staining pattern of cells and tissues when using haematoxylin and eosin stains. Specifically, the name refers to structures which "love" acid, and take it up readily.

It describes the microscopic appearance of cells and tissues, as seen down the microscope, after a histological section has been stained with an acidic dye. The most common such dye is eosin, which stains acidophilic organisms red and is the source of the related term eosinophilic.

See also

• Anterior pituitary acidophil
• Basophilic
• Oxyphil cell
• Eosinophil granulocyte

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