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Apo or APO may refer to: - African Press Organization
- Acting Pilot Officer, the lowest commissioned grade in the Royal Air Force
- Acute Pulmomary Oedema, fluid accumulation on the lungs
- African Political Organization, a Coloured political organization in early twentieth century South Africa
- Alpha Phi Omega, a U.S. service fraternity
- Apo, a god of mountains in Inca mythology
- Serok Apo or Abdullah calan, Kurdistan Workers Party leader
- Apochromat, a type of photographic or other lens
- Apoprotein, a protein without its bound cofactor
- Apotex, Canadian pharmaceutical company, producer of generic drugs
- Application Performance Optimization
- Army Post Office: chiefly U.S. Army and U.S. Air Force postal services. Also See military mail
- Association for Professional Observers, an association of fisheries observers
- , a political protest movement in West Germany during the 1960s and 1970s
- Authorized Personnel Only, a fictional black ops unit on Alias
- After Peak Oil, an epoch used in dating years following the estimated Peak of Global Oil Production
Places - Apo Island, a volcanic island in the Philippines
- Mount Apo, a stratovolcano on the island of Mindanao in the Philippines
- Kara River or Apo, a tributary of the Danube in the Banat region of Serbia and Romania
- Apo-eup, an eup in Gimcheon, Gyeongsangbuk-do, central South Korea
- Apache Point Observatory, an observatory in the Sacramento Mountains in Sunspot, New Mexico, U.S.
Music Noble Title - see Datu, one of the traditional Philippine noble titles used along with Datu, Lakan and Sultan, depending on the prestige and wealth of the nobleman.
See also cs:APO de:APO (Begriffskl rung) es:APO eo:APO fr:APO it:APO nl:Apo ja:APO pl:APO pt:Apo ro:APO sv:APO tl:Apo
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