Arroyo Seco (Spanish: "dry creek") may refer to:

Argentina:

• Arroyo Seco, Santa Fe

Mexico:

• Arroyo Seco, Quer taro

United States:

• Arroyo Seco, New Mexico
• Arroyo Seco (Alameda County), a watercourse in Alameda County, California
• Arroyo Seco (Los Angeles County), a watercourse in Los Angeles County, California
• Arroyo Seco (Salinas River), a watercourse in Monterey County, California
  • Arroyo Seco AVA, California wine region in Monterey County
• Arroyo Seco Creek, a watercourse in Sonoma County, California
• Arroyo Seco Parkway, the first California freeway
• Arroyo Seco Raceway, a paved racetrack near Deming, New Mexico

Uruguay:

• Arroyo Seco, neighbourhood of Montevideo

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